November 2019
In October of 2019, the EEG activity was evaluated and compared to the plasma level data of compound K9MGP. The appearance of beta wave activity in the EEG is associated with a cessation of seizure activity. This was observed when the plasma levels of K9MGP reached and passed 50 nanograms/milliliter. The IM dose of 0.1 mg/Kg reached this level between 2-4 minutes following administration. The IM dose of 0.3 mg/Kg reached this level between 1-1.2 minutes following drug administration. The IV dose reached this level virtually instantaneously.